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Spontaneous subarachnoid hemorrhage (SAH) remains a life-threatening type of hemorrhagic stroke. Astrocytes are key cellular responders after SAH. We designed the current study to elucidate the global astrocyte reaction…
Post-mortem tau pathology is frequently observed in Parkinsonâs disease (PD) using immunohistochemistry (IHC) to measure large inclusions. However, small protein aggregates that precede inclusions are considered a…
Correction to: Molecular Psychiatry https://doi.org/10.1038/s41380-026-03560-0; published online 02 April 2026 Following publication of this article, the authors identified an error in the corresponding authorship…
Voltage-gated sodium channels regulate neuronal excitability and synaptic transmission in the postnatal and adult brain. The gene SCN2A, encoding the sodium channel Nav1.2, regulates synaptic development and variants in…
Brain health is central to Africaâs development, but current financing and policy frameworks remain poorly matched to the scale and distribution of need. Upstream economic risks, such as poverty, inequality, food…
In order to improve their performance, musicians devote thousands of hours to practising their instrument. However, how practise shapes the behaviour of muscles involved in music-making is not yet fully understood. Using…
Emotion dysregulation (ED) is a core transdiagnostic feature of several psychiatric disorders, including borderline personality disorder, bipolar disorder, and attention-deficit/hyperactivity disorder. These ED disorders…
What makes some people willing to help strangers at a personal cost, while others are more hesitant or selective? Early life adversity - such as neglect or abuse - may shape how we respond to strangers in need later in…
Social anxiety (SA) frequently co-occurs with autism spectrum disorder (ASD), but it remains unclear whether SA in ASD reflects greater symptom severity or a distinct subtype. Across two complementary studies, we…
Force of Nature: Understanding Evolution’s Deepest Logic — and Putting It to Use Owen D. Jones W. W. Norton (2026) From antimicrobial resistance and vaccines to drugs design and even policymaking, evolution is…
Physically and visually disabled persons in nursing-home based care face numerous challenges and are a vulnerable population subjected to environmental barriers and restrictions potentially leading to poor quality of…
Historically, personality traits have been viewed as highly stable and âset like plasterâ once people reach adulthood. Although decades of research have refuted this claim, it remains unclear how much personality…
The interplay between sleep, light exposure, and circadian rhythms is critical for health, yet it remains inadequately described in the everyday lives of parents with young infants. Prior work has focused mainly on…
Radical climate protests have been theorized to shape perceptions of moderate climate groups, a dynamic known as the radical flank effect (RFE). We examine this phenomenon through a longitudinal analysis of German media…
As humanoid robots and artificial intelligence technologies advance, people’s concerns about non-human entities becoming like or replacing humans are increasing. However, considering the prospect of coexistence with…
Children and youth face rising mental health challenges in an increasingly digital world. Universal Tier 1 digital mental health interventions (DMHIs)—low-intensity, high-reach supports for non-clinical populations—have…
Speaking remains a persistent challenge for Saudi EFL learners, as large classes, limited exposure, and speaking anxiety restrict opportunities for practice. This quasi-experimental study examined whether…
Peer relationships are closely linked to academic development, but the distinct roles of best friend (BF) and fixed peer groups (PGs) across developmental stages remain unclear. Clarifying these patterns is important for…
This study investigates the differential associations between AI-integrated entrepreneurship education (AIEE), traditional entrepreneurship education (TEE), and college studentsâ entrepreneurial intention (EI) using…
This scoping review maps literature for use of ketamine or esketamine with psychotherapy for depression or depressive symptoms. Forty-seven studies were identified including 4/47 (9%) randomized controlled trials, 4/47…
This study evaluated psychological resilience, COVID-19–related anxiety, and COVID-19 vaccine hesitancy, together with factors independently associated with these outcomes, among academic professionals during the…
Despite growing public concern regarding the marine discharge of Fukushima treated contaminated water (FTCW), trust aspects related to risk perception remain underexplored. We used a nationally representative survey in…
Multimodal Emotion Recognition in Conversation (MERC) has emerged as a prominent research focus, aiming to accurately interpret emotional states by analyzing textual, audio, and visual modalities within dynamic…
Existing literature often conceptualises emigration as a response to dissatisfaction with the societal status quo, particularly when attempts to voice change are perceived as ineffective. Yet, even under conditions of…
This study explores the associations between artificial intelligence (AI) usage patterns and perceived critical thinking among university students in China, with a focus on three types of AI use: Information Retrieval…
Although media use has long played a central role in research on political attitudes, its relationship with corruption perceptions remains insufficiently understood. Drawing on the Differential Susceptibility to Media…
Unraveling the phenotypic complexity of autism is essential for advancing our understanding of its underlying biology, developmental trajectories, and diverse clinical presentations. Traditional classifications of…
Background Dissociative symptoms arise in reaction to significant stress and are common in post-traumatic stress disorder (PTSD). Methods We longitudinally investigated the course of dissociative symptoms in psychiatric…
Opioid use disorder (OUD) is part of the broader spectrum of substance use disorders often complicated by psychiatric symptoms such as depression, anxiety, PTSD (Post-Traumatic Stress Disorder), and sleep disturbances…
Background There has been limited research among family physicians (FPs) in Türkiye regarding smoking cessation and few studies have examined their perceptions of e-cigarettes as smoking cessation aids. This study aimed…
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